Health News

Health History - Timeline of Discovery

Timeline - Description

400 BC - Disease Theory - Hippocrates

1250 - Magnifying glass - China

1285 - Eye glasses - Alessandro de Spina

1538 - Optic nerve - Constanzo Varolio

1540 - Artificial limbs - Ambroise Pare

1545 - Basic surgical principles - Surgery

1590 - Compound Microscope - Zacharias Jannsen

1611 - Double convex microscope - Johannes Kepler

1612, 1616 - Thermometer - Santorio Santorio, Function of heaert and complete cirulation of blood

1650 - Lymph glands - Olof Rudbeck

1658 - Red blood cells - Jan Swammerdam

1666 - Quinine - Vaccine

1667 - Blood transfusion - Jean Baptiste Denis, France

1683 - Bacteria, Spermatzoa - Anto van Leeuwenhoek

1695 - Epsom salt - Nehemiah Grew

1736 - Scarlet fever - William Douglass

1740 - Curare (drug) - Charles Marie de lacondamine

1747 - Scurvy Cure - James Lind

1780 - Artificial insemination - Lazzaro Spallanzani

1784 - Bifocal lenses - Benjamin Franklin

1785 - Digitalis - Vaccine

1796 - Smallpox vaccine - Edward Jenner

1799 - Smallpox vaccine

1805 - Morphine - Friedrich Wilhelm Adam Serturner

1810 - Homeopathy - Samuel Hahnemann

1816 - Stethoscope - Rene Theophile Hyacinthe Laennec

1817 - Parkinson's disease - James Parkinson

1817 - Dental plate - Anthony Plantson

1819 - Dental amalgam - Charles Bell

1820 - Diphteria - Pierre Fidele Bretonneau

1825 - Binocular telescope - J.P Lemiere

1828 - Stethoscope with earpiece - Pierre Adolphe Poirry

1834 - Nervous reflex - Marshall Hall

1837 - Braille reading system - Louis Braille

1842 - Ether anesthesia, General anesthesia - Crawford Williamson Long

1843 - Puerperal fever

1844 - Nitrous oxide anesthesia - Horace Wells and Gardner Q. Colton

1846 - Use of anesthesia in surgery - William Morton

1847 - Chloroform anes - Jacob Bell and James Young Simpson

1850 - Germ Theory

1853 - Hypodermic syringe - Charles Gabriel Pravaz and Alexander Wood

1855 - Spinal anestesia - J.L Corning

1861 - Speech center of brain - Pierre Paul Broca

1865 - Genetics - Gregor Johann Mendel

1867 - Formaldehyde - August Wilhelm von Hofmann

1867 - Antiseptic practices in hospitals - Joseph Lister

1870 - Antiseptic surgery - Surgery

1877 - Liquid oxygen - Louis Paul Cailletet and Raoul Pictet

1880 - Hearing aid - R. G Rhodes

1882 - Tuberculosis and cholera germs - Robert Koch

1884 - Local anesthesia - K Koller

1886 - Appendicitis

1887 - Electro cardiogram - Augustus Desire Walker

1887 - Contact lenses - Eugen A. Frick

1890 - Insect-borne disease transmission; scurvy; heat-killed vaccines

1891 - Diptheria antitoxin - Emil Adolf van Behring and Shibasaburo Kitsato

1892 - Cholera vaccine - Waldemar Mordecai Wolff Haffkine

1895 - X rays - Wilhelm Konrad von Roetgen

1897 - Cause of malaria (mosquito) - Ronald Ross

1897 - Digestion physiology - Ivan Petrovic Pavlov

1898 - Vitamin deficiency diseases - Christian Eijkman

1899 - Aspirin

1901 - Blood groups - Karl Landsteiner

1902 - Hormones - William Maddock Bayliss and Ernest H. Starling

1906 - ECG

1909 - IUD (intrauterine device) - R. Richter

1909 - Typhus fever body louse - Charles Jules Henri Nicolle

1910 - Tumor virus - Rancis Peyton Rous

1910 - Gene theory of heredity - Thomas Morgan

1911 - Salvarsan

1912 - Diffraction of X-rays - Max Theodor Felix von Laue

1912 - Thiamine (vitamin B1) - Casimir Funk

1913 - Vitamin A - Thomas Osborne, L. Mendel, Elmer, M. Davis

1914 - Electrocardiograph

1918 - Vitamin D - Edward Mellanby

1921 - Insulin - Frederick Banting and Charles Best

1922 - Insulin - Founding of Joslin Diabetes Center.

1922 - Vitamin E - Herbet Evans

1923 - Heart valve surgery

1925 - Three-flanged nail

1927 - Iron Lung - Philip Drinker and Louis Shaw

1927 - Sex hormones - Bernhard Zondek and Selmar Ascheim

1927 - syphilis test

1928 - Vitamin C - Albert von Nagyrapolt

1929 - Electron microscope - Max Knoll and Ernst Ruska

1929 - Brain wave electroencephalograph - Hans Berger

1929 - First polio patient saved

1930 - Overactive thyroid; rickets; osteoporosis

1931 - Blood bank - Sergei Sergeivitch

1932 - TEM, Defibrillator - William Bennet Kouwenhoven

1933 - Riboflavin (vitamin B2), Patnothenic acid - Richard Kuhn, Roger Williams

1933 - Intracellular fluid and electrolytes

1934 - Vitamin K, Vitamin B6 - Carl Peter Henrik Dam and Edward Doisy

1935 - Electronic hearing aid - Edwin Steven

1935 - Sulfonamides

1937 - Niacin - Conrad Elvehjem

1938 - A cardiac Catherization

1938 - Folic acid - P.L Day

1938 - Corrective heart surgery for children

1942 - Vitamin H (biotin) - Vicent du Vigneaud

1942 - Burn treatment; blood bank; emergency-response plans

1945 - Artificial kidney, Kidney dialysis machine - Willem Kolff

1945 - Pap smear

1946 - Rh disease

1947 - Coenzyme A - Fritz Lipman

1947 - Vitamin B12 for anemia - Karl A Folkers

1947 - Artificial kidney; pediatric remission of acute

1948 - Stenotic mitral heart valves

1949 - Vaccine culture technique; cortisone; White classification

1950 - Chlorpromaine (tranquilizer) - Paul Charpentier

1950 - Wilms tumor

1951 - Oral contraceptive pill - Gregory Pincus, Min Chang, John Rock, and Carl Djerassi

1951 - Coronary artery bypass

1951 - Brain proteolipids

1952 - Artificial heart valve - Charles Hufnagel

1952 - Kidney transplant

1953 - DNA - Francis Crick and James Watson

1954 - Oral contraceptives

1955 - RNA - Severo Ochoa

1955 - Polio vaccine - Jonas Salk

1955 - Ultra sound - Leskell

1955 - Kidney transplant

1956 - Amniocentesis - St. Mary's Hospital

1956 - Human growth hormone - Choh Hao Li

1956 - Plastic contact lens - Norman Bier

1957 - Polio vaccine (live) - Albert Sabin

1957 - Fiber optic Endoscopy

1957 - Artificial heart pacemaker - Clarence Lillehie

1957 -Brain structures

1959 - Librium

1960 - Primary healthcare physicians revisited - Platelets; proton beam therapy; implantable cardiac pacemaker

1962 - Nethalide

1962 - Human limb reattachment; heart rhythm restoration

1964 - Laser eye surgery - H Vernon Ingram

1964 - Human blood storage

1965 - Rubella vaccine - Pal Parkman and Harry Meyer

1965 - Pan-retinal coagulation

1967 - Heart transplant

1968 - Hemoglobin molecule structure - Max Perutz

1968 - Telemedicine

1969 - Anti body chemical and molecular structure - Rodney Porter

1969 -Intra-aortic balloon catheter

1970 - Human oncogene; positron emission tomography (PET) scan

1972 - Artificial hip - John Charnley

1972 - Enkephalin (brain chemical) - John Hughes

1973 - CT Scanner - Allan Cormack and Godfrey N Hounsfield

1973 - Rocombinant DNA - Paul Berg

1973 - Noninvasive fetal heart monitoring

1974 - Photo-chemotherapy

1975 - Monoclonal antibodies - Cesar Milstein

1976 - Coronary angioplasty

1976 - Insulin resistance receptors

1977 - Virus particle structure

1978 - Human insulin - Genetech

1978 - Test tube baby - Patrick Steptoe and Robert Edwards

1978 - Prenatal DNA sequencing

1979 - Single cell protein process - ICI Agriculture

1979 - Shock wave lithotripsy

1979 - Magnetic resonance imaging (MRI)

1980 - HIV/AIDS

1981 - MRI Scanner - Thorn EMI Research

1981 - AIDS - CDC

1981 - Hep B immunization (HBV)

1981 - Artificial skin; premature puberty reversal

1982 - Cancer genes - Robert Weinberg and Mario Barbacid

1982 - Artificial heart -Robert Jarvik

1983 - Congenital birthmark treatment; Huntington's

1984 - Gene cloning - NIH

1984 - Isolation of AIDs - Robert Gallo

1984 - Human insulin

1984 - Oncomouse; skin replacement; TIMI

1985 - Blood clotting - Genetech

1985 - PET Scanner - Michael Phelps

1985 - Anxiety chemical - Alessandro Guidotti and Erminion Costa

1985 - Cloned leprosy gene vaccine - Ron Davis

1985 - PTM Microscope - Jame van House and Arthur Rich

1985 - Kawasaki disease retrovirus; Alzheimer's disease

1986 - DNA fingerprinting - Alec Jeffreys

1986 - Synthetic skin - G Gallico

1986 - Ziduvudine

1987 - Alzheimer's disease gene - NIH

1987 - Fetal tissue transplant

1987 - Early-onset Alzheimer's gene; Duchenne muscular dystrophy gene

1988 - Laser tattoo removal

1989 - Foreign gene into human - NIH

1989 - Tumor blood vessel growth compound

1990 - Proteasome-inhibiting cancer therapy

1991 - X-ray of human brain recalling a word - Dr. Marcus Raichle

1991 - IntronA - Hep B Medication

1992 - Diphtheria toxin structure; amyloid beta

1993 - Neovascular macular degeneration; microRNAs; paralyzed vocal cord surgical method; colon cancer gene; VEGF molecule

1994 - PR-39 molecule - Amino Acid Sequence of PR-39. Isolation From Pig Intestine of a New Member of the Family of Proline-Arginine-Rich Antibacterial Peptides. The continued investigation of these antibacterial peptides has now yielded another antibacterial peptide with high activity against both E. coli and Bacillus megaterium. Amino acid analysis showed a very high content of proline (49 mol%) and arginine (26 mol%), an intermediate level of phenylalanine and low levels of leucine, tyrosine, isoleucine, and glycine.

1995 - Triple-organ transplant; kidney disease blood glucose levels

1996 - Alzheimer's treatments; immune system advances

1997 - p73 gene; asprin

1998 - Epivir HBV, Zeffrx, Hep B Medication

1998 - Adult live-donor liver transplant

1999 - Fluorescent molecular probes

2000 - Human genome 23,000 genes

2001 - Circadian clock

2002 - Hepsera - Hep B Medication

2002 - Rheumatoid arthritis pathway; C- reactive

2003 - Multidrug-resistant tuberculosis treatment; source of preeclampsia

2004 - Blood stem cells; protein transfer

2005 - Pegasys - Hep B Medication

2005 - Baraclude- Hep B Medication

2005 - Prenatal nutrition; herpes vaccine candidate

2006 - Tyzeka, Sebiro - Hep B Medication

2006 - Cholesterol mechanism; DNA sequencing techniques

2007 - Cellular switch; rheumatoid arthritis gene; brown-fat cell switch

2008 - Viread - Hep B Medication

2008 - RIPKI inhibitors; metastatic melanoma

2009 - LIN28 protien; RNA interference; cancer cells' starvation; brown fat

2010 - Enhancer transcription

2011 - Kidney failure markers; cancer cell vulnerability; global health care budget models

2012 - Tumor suppressor gene p53; ancient migration; infectious disease diagnostics

2013 - Cardiac hypertrophy reversal; cathepsin k pathways

2014 - Hematopoietic stem cells; pancreatic stem cells

2015 - Bioartificial replacement limb; PD-1 pathway; The Lancet Commission on Global Surgery; pseudogene; damaged protein disposal; multiple sclerosis; somatic mutations; deafness gene therapies

2016 - Sigma-1 receptor structure; Zika vaccine candidate; circadian rhythm- bipolar disorder link; microbiome

2017 - Rheumatoid arthritis; precision treatments

2018 - Widespread Adoption of ELECTRONIC HEALTH RECORDS

2019 - COVID 19 - Discovery, diagnostic testing

2020 - COVID 19 - Remedesvir, hydroxychloroquine, Favipiravir

Bibliography

New York Public Library Desk Reference

Hepatitis B Initiative

Coronavirus Articles