Health History
Health History - Timeline of Discovery
Timeline - Description
400 BC - Disease Theory - Hippocrates
1250 - Magnifying glass - China
1285 - Eye glasses - Alessandro de Spina
1538 - Optic nerve - Constanzo Varolio
1540 - Artificial limbs - Ambroise Pare
1545 - Basic surgical principles - Surgery
1590 - Compound Microscope - Zacharias Jannsen
1611 - Double convex microscope - Johannes Kepler
1612, 1616 - Thermometer - Santorio Santorio, Function of heaert and complete cirulation of blood
1650 - Lymph glands - Olof Rudbeck
1658 - Red blood cells - Jan Swammerdam
1666 - Quinine - Vaccine
1667 - Blood transfusion - Jean Baptiste Denis, France
1683 - Bacteria, Spermatzoa - Anto van Leeuwenhoek
1695 - Epsom salt - Nehemiah Grew
1736 - Scarlet fever - William Douglass
1740 - Curare (drug) - Charles Marie de lacondamine
1747 - Scurvy Cure - James Lind
1780 - Artificial insemination - Lazzaro Spallanzani
1784 - Bifocal lenses - Benjamin Franklin
1785 - Digitalis - Vaccine
1796 - Smallpox vaccine - Edward Jenner
1799 - Smallpox vaccine
1805 - Morphine - Friedrich Wilhelm Adam Serturner
1810 - Homeopathy - Samuel Hahnemann
1816 - Stethoscope - Rene Theophile Hyacinthe Laennec
1817 - Parkinson's disease - James Parkinson
1817 - Dental plate - Anthony Plantson
1819 - Dental amalgam - Charles Bell
1820 - Diphteria - Pierre Fidele Bretonneau
1825 - Binocular telescope - J.P Lemiere
1828 - Stethoscope with earpiece - Pierre Adolphe Poirry
1834 - Nervous reflex - Marshall Hall
1837 - Braille reading system - Louis Braille
1842 - Ether anesthesia, General anesthesia - Crawford Williamson Long
1843 - Puerperal fever
1844 - Nitrous oxide anesthesia - Horace Wells and Gardner Q. Colton
1846 - Use of anesthesia in surgery - William Morton
1847 - Chloroform anes - Jacob Bell and James Young Simpson
1850 - Germ Theory
1853 - Hypodermic syringe - Charles Gabriel Pravaz and Alexander Wood
1855 - Spinal anestesia - J.L Corning
1861 - Speech center of brain - Pierre Paul Broca
1865 - Genetics - Gregor Johann Mendel
1867 - Formaldehyde - August Wilhelm von Hofmann
1867 - Antiseptic practices in hospitals - Joseph Lister
1870 - Antiseptic surgery - Surgery
1877 - Liquid oxygen - Louis Paul Cailletet and Raoul Pictet
1880 - Hearing aid - R. G Rhodes
1882 - Tuberculosis and cholera germs - Robert Koch
1884 - Local anesthesia - K Koller
1886 - Appendicitis
1887 - Electro cardiogram - Augustus Desire Walker
1887 - Contact lenses - Eugen A. Frick
1890 - Insect-borne disease transmission; scurvy; heat-killed vaccines
1891 - Diptheria antitoxin - Emil Adolf van Behring and Shibasaburo Kitsato
1892 - Cholera vaccine - Waldemar Mordecai Wolff Haffkine
1895 - X rays - Wilhelm Konrad von Roetgen
1897 - Cause of malaria (mosquito) - Ronald Ross
1897 - Digestion physiology - Ivan Petrovic Pavlov
1898 - Vitamin deficiency diseases - Christian Eijkman
1899 - Aspirin
1901 - Blood groups - Karl Landsteiner
1902 - Hormones - William Maddock Bayliss and Ernest H. Starling
1906 - ECG
1909 - IUD (intrauterine device) - R. Richter
1909 - Typhus fever body louse - Charles Jules Henri Nicolle
1910 - Tumor virus - Rancis Peyton Rous
1910 - Gene theory of heredity - Thomas Morgan
1911 - Salvarsan
1912 - Diffraction of X-rays - Max Theodor Felix von Laue
1912 - Thiamine (vitamin B1) - Casimir Funk
1913 - Vitamin A - Thomas Osborne, L. Mendel, Elmer, M. Davis
1914 - Electrocardiograph
1918 - Vitamin D - Edward Mellanby
1921 - Insulin - Frederick Banting and Charles Best
1922 - Insulin - Founding of Joslin Diabetes Center.
1922 - Vitamin E - Herbet Evans
1923 - Heart valve surgery
1925 - Three-flanged nail
1927 - Iron Lung - Philip Drinker and Louis Shaw
1927 - Sex hormones - Bernhard Zondek and Selmar Ascheim
1927 - syphilis test
1928 - Vitamin C - Albert von Nagyrapolt
1929 - Electron microscope - Max Knoll and Ernst Ruska
1929 - Brain wave electroencephalograph - Hans Berger
1929 - First polio patient saved
1930 - Overactive thyroid; rickets; osteoporosis
1931 - Blood bank - Sergei Sergeivitch
1932 - TEM, Defibrillator - William Bennet Kouwenhoven
1933 - Riboflavin (vitamin B2), Patnothenic acid - Richard Kuhn, Roger Williams
1933 - Intracellular fluid and electrolytes
1934 - Vitamin K, Vitamin B6 - Carl Peter Henrik Dam and Edward Doisy
1935 - Electronic hearing aid - Edwin Steven
1935 - Sulfonamides
1937 - Niacin - Conrad Elvehjem
1938 - A cardiac Catherization
1938 - Folic acid - P.L Day
1938 - Corrective heart surgery for children
1942 - Vitamin H (biotin) - Vicent du Vigneaud
1942 - Burn treatment; blood bank; emergency-response plans
1945 - Artificial kidney, Kidney dialysis machine - Willem Kolff
1945 - Pap smear
1946 - Rh disease
1947 - Coenzyme A - Fritz Lipman
1947 - Vitamin B12 for anemia - Karl A Folkers
1947 - Artificial kidney; pediatric remission of acute
1948 - Stenotic mitral heart valves
1949 - Vaccine culture technique; cortisone; White classification
1950 - Chlorpromaine (tranquilizer) - Paul Charpentier
1950 - Wilms tumor
1951 - Oral contraceptive pill - Gregory Pincus, Min Chang, John Rock, and Carl Djerassi
1951 - Coronary artery bypass
1951 - Brain proteolipids
1952 - Artificial heart valve - Charles Hufnagel
1952 - Kidney transplant
1953 - DNA - Francis Crick and James Watson
1954 - Oral contraceptives
1955 - RNA - Severo Ochoa
1955 - Polio vaccine - Jonas Salk
1955 - Ultra sound - Leskell
1955 - Kidney transplant
1956 - Amniocentesis - St. Mary's Hospital
1956 - Human growth hormone - Choh Hao Li
1956 - Plastic contact lens - Norman Bier
1957 - Polio vaccine (live) - Albert Sabin
1957 - Fiber optic Endoscopy
1957 - Artificial heart pacemaker - Clarence Lillehie
1957 -Brain structures
1959 - Librium
1960 - Primary healthcare physicians revisited - Platelets; proton beam therapy; implantable cardiac pacemaker
1962 - Nethalide
1962 - Human limb reattachment; heart rhythm restoration
1964 - Laser eye surgery - H Vernon Ingram
1964 - Human blood storage
1965 - Rubella vaccine - Pal Parkman and Harry Meyer
1965 - Pan-retinal coagulation
1967 - Heart transplant
1968 - Hemoglobin molecule structure - Max Perutz
1968 - Telemedicine
1969 - Anti body chemical and molecular structure - Rodney Porter
1969 -Intra-aortic balloon catheter
1970 - Human oncogene; positron emission tomography (PET) scan
1972 - Artificial hip - John Charnley
1972 - Enkephalin (brain chemical) - John Hughes
1973 - CT Scanner - Allan Cormack and Godfrey N Hounsfield
1973 - Rocombinant DNA - Paul Berg
1973 - Noninvasive fetal heart monitoring
1974 - Photo-chemotherapy
1975 - Monoclonal antibodies - Cesar Milstein
1976 - Coronary angioplasty
1976 - Insulin resistance receptors
1977 - Virus particle structure
1978 - Human insulin - Genetech
1978 - Test tube baby - Patrick Steptoe and Robert Edwards
1978 - Prenatal DNA sequencing
1979 - Single cell protein process - ICI Agriculture
1979 - Shock wave lithotripsy
1979 - Magnetic resonance imaging (MRI)
1980 - HIV/AIDS
1981 - MRI Scanner - Thorn EMI Research
1981 - AIDS - CDC
1981 - Hep B immunization (HBV)
1981 - Artificial skin; premature puberty reversal
1982 - Cancer genes - Robert Weinberg and Mario Barbacid
1982 - Artificial heart -Robert Jarvik
1983 - Congenital birthmark treatment; Huntington's
1984 - Gene cloning - NIH
1984 - Isolation of AIDs - Robert Gallo
1984 - Human insulin
1984 - Oncomouse; skin replacement; TIMI
1985 - Blood clotting - Genetech
1985 - PET Scanner - Michael Phelps
1985 - Anxiety chemical - Alessandro Guidotti and Erminion Costa
1985 - Cloned leprosy gene vaccine - Ron Davis
1985 - PTM Microscope - Jame van House and Arthur Rich
1985 - Kawasaki disease retrovirus; Alzheimer's disease
1986 - DNA fingerprinting - Alec Jeffreys
1986 - Synthetic skin - G Gallico
1986 - Ziduvudine
1987 - Alzheimer's disease gene - NIH
1987 - Fetal tissue transplant
1987 - Early-onset Alzheimer's gene; Duchenne muscular dystrophy gene
1988 - Laser tattoo removal
1989 - Foreign gene into human - NIH
1989 - Tumor blood vessel growth compound
1990 - Proteasome-inhibiting cancer therapy
1991 - X-ray of human brain recalling a word - Dr. Marcus Raichle
1991 - IntronA - Hep B Medication
1992 - Diphtheria toxin structure; amyloid beta
1993 - Neovascular macular degeneration; microRNAs; paralyzed vocal cord surgical method; colon cancer gene; VEGF molecule
1994 - PR-39 molecule - Amino Acid Sequence of PR-39. Isolation From Pig Intestine of a New Member of the Family of Proline-Arginine-Rich Antibacterial Peptides. The continued investigation of these antibacterial peptides has now yielded another antibacterial peptide with high activity against both E. coli and Bacillus megaterium. Amino acid analysis showed a very high content of proline (49 mol%) and arginine (26 mol%), an intermediate level of phenylalanine and low levels of leucine, tyrosine, isoleucine, and glycine.
1995 - Triple-organ transplant; kidney disease blood glucose levels
1996 - Alzheimer's treatments; immune system advances
1997 - p73 gene; asprin
1998 - Epivir HBV, Zeffrx, Hep B Medication
1998 - Adult live-donor liver transplant
1999 - Fluorescent molecular probes
2000 - Human genome 23,000 genes
2001 - Circadian clock
2002 - Hepsera - Hep B Medication
2002 - Rheumatoid arthritis pathway; C- reactive
2003 - Multidrug-resistant tuberculosis treatment; source of preeclampsia
2004 - Blood stem cells; protein transfer
2005 - Pegasys - Hep B Medication
2005 - Baraclude- Hep B Medication
2005 - Prenatal nutrition; herpes vaccine candidate
2006 - Tyzeka, Sebiro - Hep B Medication
2006 - Cholesterol mechanism; DNA sequencing techniques
2007 - Cellular switch; rheumatoid arthritis gene; brown-fat cell switch
2008 - Viread - Hep B Medication
2008 - RIPKI inhibitors; metastatic melanoma
2009 - LIN28 protien; RNA interference; cancer cells' starvation; brown fat
2010 - Enhancer transcription
2011 - Kidney failure markers; cancer cell vulnerability; global health care budget models
2012 - Tumor suppressor gene p53; ancient migration; infectious disease diagnostics
2013 - Cardiac hypertrophy reversal; cathepsin k pathways
2014 - Hematopoietic stem cells; pancreatic stem cells
2015 - Bioartificial replacement limb; PD-1 pathway; The Lancet Commission on Global Surgery; pseudogene; damaged protein disposal; multiple sclerosis; somatic mutations; deafness gene therapies
2016 - Sigma-1 receptor structure; Zika vaccine candidate; circadian rhythm- bipolar disorder link; microbiome
2017 - Rheumatoid arthritis; precision treatments
2018 - Widespread Adoption of ELECTRONIC HEALTH RECORDS
2019 - COVID 19 - Discovery, diagnostic testing
2020 - COVID 19 - Remedesvir, hydroxychloroquine, Favipiravir
2020 - COVID 19 - Vaccines: Pfizer, Moderna, Johnson and Johnson
Bibliography
New York Public Library Desk Reference
Hepatitis B Initiative
Coronavirus Articles